产品货号:
Z23987
中文名称:
PPARD抗体
英文名称:
Anti-PPARD Antibody (C-term)
产品规格:
80μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PPARD Antibody (C-term) |
指标别名 | FAAR;NR1C2;NUC1;NUCI;NUCII;Nuclear hormone receptor 1;PPAR beta;PPAR delta;PPARB;PPARD |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | PPARD |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This PPARD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from the C-terminal region of human PPARD. |
计算分子量 | 50kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family.PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells.PPARs mediate a variety of biological processes,and may be involved in the development of several chronic diseases,including diabetes,obesity,atherosclerosis,and cancer.This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma.It may function as an integrator of transcription repression and nuclear receptor signaling.The expression of this gene is found to be elevated in colorectal cancer cells.The elevated expression can be repressed by adenomatosis polyposis coli (APC),a tumor suppressor protein related to APC/beta-catenin signaling pathway.Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum,lipid metabolism,and epidermal cell proliferation.Alternate splicing results in multiple transcript variants. |
Uniprot ID | Q03181 |
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